Kyle Isbel went 3-for-4 with a homer and two RBIs to lead the Kansas City Royals to a 4-2 victory over the visiting Minnesota Twins on Monday night.Michael Lorenzen pitched six solid innings and Vinny Pasquantino and Bobby Witt Jr. drove in one run apiece as the Royals won the opener of the four-game set.Willi Castro and Harrison Bader drove in runs for the Twins, who lost for the third time in their last four games. Bader and Matt Wallner had two hits apiece for Minnesota.Lorenzen (1-1) allowed one run and five hits. He struck out three and didn’t walk a batter while helping Kansas City win for the third time in its last four games.Hunter Harvey and Lucas Erceg tossed scoreless innings before Royals closer Carlos Estevez ran into trouble in the ninth.Estevez hit Ty France on the elbow with one out then walked Castro with two out before Bader lined a single into left center to score France. Estevez then retired pinch hitter Edouard Julien on a grounder to second to record his third save.Minnesota’s Simeon Woods Richardson (0-1) was touched up for four runs and eight hits over 5 2/3 innings. He struck out six and walked four.The Royals moved ahead to stay by pushing across two runs in the second inning.